Objective To investigate the clinical effect of total pancreatectomy in the treatment of advanced pancreatic cancer.
Methods Clinical data of 9 TP patients administered were analyzed retrospectively in the pancreatic center of Ruijin Hospital affiliated to Shanghai Jiaotong University Medical College from June 2019 to June 2020.The clinical effect was discussed by analyzing the data of preoperative general data,operation time,intraoperative bleeding volume,intraoperative portal vein occlusion time and postoperative complications.
Results Total pancreatectomy plus jejunostomy was successfully performed in 9 patients,of which 4 patients underwent vascular resection and reconstruction due to pancreatic tumor involvement of portal vein/superior mesenteric vein.The operation time of 9 patients was 300~540 min,with an average of (385±55)min.The intraoperative blood loss ranged from 200 to 1 800 ml,with an average of (475±205)ml.The intraoperative time of portal vein occlusion was 19~45min,with an average of (26±7)min.The postoperative hospital stay was 12~35 days,with an average of (17±5)days.The most common complication after TP was postoperative fragile diabetes (7 cases),followed by postoperative gastric emptying disorder (2 cases),abdominal hemorrhage (1 case),biliary fistula (1 case),and colon fistula (1 case).After 6 months of follow-up,1 patient died,1 patient had liver metastasis,1 patient had multiple systemic metastasis,the remaining 5 patients had good survival.〖WT5”HZ〗Conclusion TP can reduce digestive tract reconstruction and complications in patients with multiple pancreatic cancer and pancreatic neuroendocrine tumors (multiple sites) and other middle and advanced pancreatic cancer.With definite surgical effect,TP can be used in patients with clinical indications.

Objective To compare the clinical effect of laparoscopic common bile duct exploration and stone extraction(LCBDE) combined with laparoscopic cholecystectomy(LC) compared with endoscopic retrograde cholangiopancreatography/endoscopic sphincterotomy(ERCP/EST) combined with laparoscopic cholecystectomy(LC) in the treatment of calcalous acute obstructive suppurative cholangitis(AOSC).
Methods The clinical data of 70 patients with calcalous AOSC in Songjiang Hospital affillated to Shanghai Jiaotong University School of Medicine were analyzed retrospectively.The cases were divided into the LCBDE+LC group(36 cases) and the ERCP/EST+LC group(34 cases) according to different treatment methods.The total operative success rate，primary operative success rate，operation time，intraoperative bleeding volume，postoperative complications rate，hospitalization time and hospitalization cost of the two groups were compared.
Results In LCBDE+LC group，the success rate of primary operation was higher than that of ERCP/EST+LC group，the length and cost of hospital stay were less than that of ERCP/EST+LC group，but the intraoperative bleeding volume was more than that of ERCP/EST+LC group.The difference was statistically significant(P＜0.05).There were no differences in the total operative success rate，operation time and postoperative complications rate between LCBDE+LC group and ERCP/EST+LC group(P＞0.05).
Conclusions Compared with ERCP/EST+LC in the treatment of calcalous AOSC，LCBDE+LC has the advantages of higher success rate of primary operation，shorter hospitalization time and lower hospitalization cost.

Objective To explore if the angle of distal common bile duct is the risk factors for PEP in beginner endoscopists without supervision.
Methods We studied a retrospective analysis of 65 patients who were perfomed ERCP from the beginner endoscopists,Patients were Classified as acute(angle≤30°)and obtuse(angle＞30°).The angle of the distal common bile duct(CBD) was measured as the angle between the lower wall of the bile duct and a vertical line on coronal view CT.Time of cannulation,The rate of pancreatic duct cannulation,Hyperamylasemia and PEP were compared between two groups.
Results ERCP success rate was 91.1 % in the acute angle group and 96.8% in the obtuse group.The cannulation time was angle group(10.05±2.67)min vs(9.35±2.79)min.The ratio of pancreatic duct cannulation was acute 50% than obtuse 32.2% angle group,Hyperamylasemia was acute 20.6%,obtuse 19.4%.The rate of PEP was acute(26.5%) than obtuse(3.22%) angle group(P = 0.018).No other severe complications(bleeding and perforation) were happened(P＜0.05).
Conclusion Obtuse distal CBD angle may have lower risk of PEP when beginner endoscopists performing ERCP.

Objective To explore the effect of fluorescence laparoscopy on the recognition of gallbladder triangle during cholecystectomy and its clinical application.
Methods A retrospective analysis of 130 cases of laparoscopic cholecystectomy(LC) was performed.The patients were divided into two groups:Group A(87 cases) and Group B(43 cases),the intraoperative and postoperative complications of the two groups were statistically analyzed.
Results All 130 patients underwent laparoscopic cholecystectomy without conversion to open surgery.In Group A,the operation time(69.75±25.64) Min,intraoperative blood loss(4.40±4.02)ml,hospital stay(4.49±1.01)D,extubation time(3.15±0.83)D,there were 5 patients with postoperative complications.The operation time(72.33±29.14) Min,intraoperative bleeding(4.19±2.83)ML,hospital stay(4.42±0.88) D and extubation time(3.09±0.72) D in Group B,no postoperative complications were found.There was no significant difference between the two groups(P>0.05)，there were no drug allergy and other drug-related complications during indocyanine green angiography.
Conclusion The application of Indocyanine Green(ICG) in laparoscopic cholecystectomy is helpful to judge the anatomy of biliary tract and has no effect on the operation time and postoperative complications,which increased the safety of surgery.

Objective To investigate the changes of serum high mobility group protein B1(HMGB1),ubiquitin C-terminal hydrolase L1(UCH-L1) and neuron-specific enolase(NSE) levels in patients with mild head injury(MHI) and correlation with prognosis.
Methods A total of 84 MHI patients admitted to our hospital(January 2017 to January 2019) were selected as the MHI group,according to the Glasgow Outcome Scale(GOS),it is divided into a poor prognosis group(n=23) and a good prognosis group(n=61),in addition,57 healthy patients who came to our hospital for physical examination during the same period were selected as the control group.Compare the serum HMGB1,UCH-L1,and NSE levels in each group,Multivariate Logistics regression analysis of factors affecting the prognosis of MHI patients,ROC analyzes the predictive value of serum HMGB1,UCH-L1,and NSE levels for the poor prognosis of MHI patients.
Results The levels of serum HMGB1,UCH-L1,and NSE in the MHI group were significantly higher than those in the control group(P<0.05).The proportion of complex injuries,complications and serum HMGB1,UCH-L1 and NSE levels in the poor prognosis group were significantly higher than those in the good prognosis group(P<0.05).Compound damage,HMGB1,UCH-L1,NSE were independent factors influencing the poor prognosis of MHI patients(P<0.05).The ROC curve shows that the AUC of HMGB1+UCH-L1+NSE predicting the poor prognosis of MHI is significantly greater than that of HMGB1,UCH-L1,NSE were predicted separately.
Conclusion The serum levels of HMGB1, UCH-L1 and NSE in MHI patients were significantly increased, which were closely related to the prognosis. Combined detection could improve the prognostic value of MHI.

Objective To summarize the experience and results of applying Hybrid technology to treat thoracoabdominal aortic diseases in our hospital.
Methods We counted 10 patients with thoracoabdominal aortic lesions admitted to our hospital from October 2016 to October 2020,including one case of thoracoabdominal aortic aneurysm and nine cases of thoracoabdominal aortic dissection.According to the extent of aortic disease involvement,visceral artery bypass surgery at the corresponding involvement site was performed first,followed by endoluminal overlapping stent repair of the aorta in one stage.The follow-up period ranged from 3 to 48 months,with a median follow-up time of 24.5 months.
Results All surgeries were successfully completed,including 10 cases of first-stage endovascular repair.The average operating time for the same operation was 8.5 h,and the average endovascular operation time was 2.0 h.There were no fatal cases 30 days after surgery,5 cases of acute kidney injury,5 cases of acute liver injury,3 cases of intestinal obstruction,and 1 case of intestinal fistula in the perioperative period.One of the patients with intestinal fistula died 3 months after surgery.By the end of follow-up,all patients had no endoleaks or paraplegia.All bypass vessels were patent and free of stenosis during the follow-up period.
Conclusion The hybridization technique is feasible for the treatment of complex thoracoabdominal aortopathy,with satisfactory near- to mid-term outcomes and long-term results awaiting further follow-up.

Objective To summarize the clinical experience of staging strategy in esophageal replacement with colon operation.
Methods Thirty-five patients who underwent esophageal replacement with colon were used staging surgery,20 patients were with esophageal cancer after subtotal gastrectomy,5 patients with recurring esophageal cancer after esophageal cancer,4 patients with thoracic stomach cancer,2 patients with tracheoesophageal fistula after esophageal carcinoma resection,2 patients with gastric necrosis after esophageal carcinoma resection,and 2 patients with esophageal fistula caused by esophageal chemical burn and scar stenosis.Among the above-mentioned patients,28 patients underwent esophageal lesion resection first,followed by elective esophageal replacement with colon;7 patients underwent esophageal replacement with colon first and then elective esophageal lesion resection.
Results All 35 patients were successfully performed staged surgery as planned,with the interval between operations ranging from 3 to 12 months.1 patient was with neck anastomotic fistula postoperative,1 with chylothorax and 2 with pulmonary infection,they were all cured after conservative treatment and discharged.After one year of follow-up,all the patients could eat normal diet and gained more weight than pre- operation.
Conclusion The staging surgical strategy applied to esophageal replacement with colon has good results and fewer complications.

Objective To evaluate the effect of real-time recognition of parathyroid gland(PG) intraoperatively by near-infrared autofluorescence imaging(NIRAF).
Methods The clinical data of 59 patients undergoing thyroid surgery from June 2020 to August 2020 were analyzed.PG was identified by naked eyes and NIRAF imaging respectively during operation.The suspected PG tissues with inconsistent identification results were tested by intraoperative immunocolloidal gold to verify.
Results A total of 79 thyroids were excised in 59 patients and 158 PGs were expected to be identified routinely ignoring uncommon number variation.However,only 144 PGs were finally confirmed,and the detection rate was 91.1%(144/158).In addition,the transplantation rate of PG was 4.4%(7/158).The detection rate of NIRAF imaging and naked eyes was 90.5%(143/158) and 86.7%(137/158) respectively,and the accuracy rate was 98.6%(143/145) and 100%(137/137) respectively,with no significant difference between them.It is worth mentioning that,the detection rate of NIRAF was 55.7%(88/158),significantly higher than naked eyes(31.6%,50/158) before the thyroid capsule anatomy（P＜0.05).
Conclusion The usage of intraoperative NIRAF imaging could significantly increase the recognition rate of PG before thyroid capsule anatomy with good predictability.Moreover,NIRAF imaging can perform intraoperative PG identification,locate PG before and after dissection,and find PG in vitro tissues.It has the advantages of intuitive,real-time,non-invasive,and no contrast agent,etc.,which can be a useful supplement for naked eyes.

Objective To investigate the deep lymph node metastasis of right recurrent laryngeal nerve(RLN) in patients with papillary thyroid carcinoma(PTC) after total thyroidectomy.
Methods 80 patients with papillary thyroid cancer in our hospital from November 2017 to November 2019 were selected.All patients were treated with total thyroidectomy combined with bilateral central lymph node dissection or right central lymph node dissection according to their condition.The right central lymph nodes were divided into superficial(Ⅵ a) and deep(Ⅵ b) according to the boundary of recurrent laryngeal nerve,The pathological samples of all lymph nodes were detected in time,and the lymph node metastasis of all patients was recorded according to the detection results.The related factors were analyzed by univariate and multivariate logistic regression analysis.
Results In this study,47 cases of PTC patients had cervical lymph node metastasis,the positive rate of lymph node metastasis was 58.8%,the average number of lymph node dissection was 13.65±2.15,the average number of positive lymph nodes was 5.61±1.17.Among them,the positive rate of deep lymph nodes of right recurrent laryngeal nerve was 15.0%,the positive rate of superficial lymph nodes was 55.0%,the positive rate of deep lymph nodes of right recurrent laryngeal nerve combined with superficial lymph nodes was 12.5%,and the positive rate of cervical lymph nodes was 6.3%.After univariate and multivariate logistic regression analysis,multiple tumors,tumor diameter > 10mm,positive lymph nodes in superficial layer of right recurrent laryngeal nerve and positive lymph nodes in lateral cervical region were independent risk factors of deep lymph node metastasis of right recurrent laryngeal nerve in PTC patients,and the difference was statistically significant(P<0.05).
Conclusion The number of tumors,tumor size,the positive superficial lymph nodes of the right recurrent laryngeal nerve and the cervical lymph nodes are the risk factors affecting the deep lymph node metastasis of the right recurrent laryngeal nerve in PTC patients.For these patients,the range of central lymph node dissection should include the deep lymph node of the right recurrent laryngeal nerve,in order to ensure the thoroughness of lymph node dissection and reduce the risk of postoperative recurrence.

Objective To summarize the clinical features,diagnosis,treatment and prognosis of sarcomatoid carcinoma of the colon.
Methods The clinicopathological data of patients with sarcomatoid carcinoma of the colon in our hospital from January 1,2013 to September 1,2020 were retrospectively collected.
Results There were 1 male and 2 female patients with an average age of 62 years(52-72 years).Serum CA19-9 was elevated in 1 case.The images showed irregular thickening of the intestinal wall with enhancement.All 3 cases underwent curative resection,1 case underwent open surgery and 2 cases underwent laparoscopic surgery.Pathological examination showed that tumor was composed with low adhesion spindle tumor cells,which expressed CAM5.2,vimentin,INI1 and BRG1.One case had gallbladder invasion and one case had lymph node metastasis.At the end of follow-up,1 case died.
Conclusion Sarcomatoid carcinoma is a special subtype of colorectal cancer with poor biological behavior.The diagnosis should be combined with histomorphology and immunohistochemistry.Curative operation is an effective way to obtain good prognosis.

Objective To evaluate the clinical effects of patella fracture treated by closed reduction and kirschner wire tension band internal fixation.
Methods From April 2018 to October 2019,40 patients with transverse patella fracture were studied.20 cases in the observation group was treated by closed reduction and kirschner wire tension band internal fixation,20 cases in the control group treated by open reduction kirschner tension band.The surgical incision length,operation time,knee visual analogue scale(VAS) and knee Lysholm score at 3 days,2 weeks,1.5 months and 6 months after surgery of 2 groups were recorded and compared.
Results Compared with the control group,the observation group had longer operation time [(64.46±7.46) min vs.(79.24±9.23) min,P＜0.05].There was no fluoroscopy in the control group,and the observation group fluoroscopy time was(15.36±2.51) min.Compared with the control group,the knee joint VAS of the observation group [(4.86±0.74) points vs.(3.54±0.86) points,(3.12±0.54) points vs.(1.65±0.62) points] at 3 days and 2 weeks after surgery had decreased(all P＜0.05),Lysholm score [(19.31±3.25) points vs.(25.41±4.23) points,(34.56±3.10) points vs.(40.25±4.56 points] had increased(all P＜0.05).The knee joint VAS [(1.14±0.31) points vs.(1.08±0.26) points,(0.63±0.19) points vs.(0.61±0.18) points] and Lysholm scores [(56.23±3.12) points vs.(59.21±2.14) points,(85.35±1.54) points vs.(84.58±1.96) points] at 1.5 months and 6 months after surgery in 2 groups had no significant differences(all P>0.05).All patients received at least 6 months of follow-up,none of 40 patients had postoperative complications such as joint infection,loosening of internal fixation,neurovascular injury and other postoperative complications.
Conclusion The closed reduction and kirschner wire tension band internal fixation can be used to treat patella fracture,which has a satisfactory clinical effect,with no incision,less trauma,early recovery and less pain.

Objective To study the value of serum D-D combined with VEGF in predicting the risk of DVT after multiple rib fractures.
Methods Ninety two patients with multiple rib fractures in our hospital were selectedand divided into the occurrence group and the non-occurrence group according to whether DVT occurred.The differences in clinical data were compared.Logistic regression analysis method to analyze the influencing factors of DVT.ROC to analyze the value on the risk of DVT.
Results The ratio of age≥60 years old,history of diabetes,history of hypertension,and history of varicose veins,serum D-D and VEGF of the occurrence group were higher than those of the non-occurring group,of which the operation time was longer than that of the non-occurring group(P＜0.05).Logistic regression analysis showed that age≥60 years old,diabetes,operation time,serum D-D,VEGF were all influencing factors of DVT(P＜0.05).ROC results showed that the AUC of serum D-D and VEGF alone and combined to predict DVT were 0.741,0.705,0.796,respectively.
Conclusion Serum D-D combined with VEGF are highly effective in predicting the occurrence of DVT after multiple rib fractures.

Objective To explore the efficacy and safety of catheter-directed thrombolysis(CDT) for early hepatic artery thrombosis(EHAT) after liver transplantation.
Methods A retrospective analysis of the clinical data of 23 patients with EHAT after liver transplantation in our department from January 2009 to November 2019.
Results All patients received CDT treatment.The average operation time of CDT catheter operation was(78±24) min.The average time of thrombolytic therapy was(87.4±22.8) h.The average dosage of urokinase was(344.5±62.3) million U.After CDT treatment,19 cases of hepatic artery thrombosis were completely dissolved,and the effective rate of CDT treatment was 82.6%(19/23).During CDT treatment,2 cases of abdominal hemorrhage(<100ml) occurred in 2 cases,and no other related complications occurred.The average follow-up time(60.4±3.7) months.The hepatic arterial patency rates of 19 patients with hepatic artery thrombosis completely dissolved at 1 year,2 years and 5 years were 94.7%(18/19)，89.5%(17/19),79%(15/19).
Conclusion CDT is a safe,effective,and minimally invasive treatment.It plays an increasingly important role in the treatment and prognosis of patients with EHAT after liver transplantation.

Objective To investigate the effects of medium-long and long chain fat emulsion propofol on endothelial system and biochemical function in patients with rectal cancer undergoing laparoscopic surgery.
Methods From May 2017 to May 2019,126 patients with rectal cancer undergoing laparoscopic surgery in our hospital were randomly divided into a long-chain fat emulsion propofol group(Lgroup) and a medium-long chain fat emulsion propofol group(M group).Anesthesia effect,incidence of adverse reactions,endothelin(ET),Calcitonin gene-related peptide(CGRP) and biochemical function of the two groups were compared.
Results After laparoscopic surgery with different dosage forms of propofol,there was no difference between the two groups in the onset time of anesthesia[(2.5±1.1)minand(2.1±0.6)min,respectly],time of complete block [(1.7±0.7)min and(1.5±0.4)min],time of recovery of spontaneous breathing[(6.5±1.9)min and(5.2±1.3)min],operation time[(275.1±33.8)minand(279.6±41.2)min)],concentration of unconsciousness[(1.9±1.0)μg/mland(2.1±0.6)μg/ml],amount of propofol consumption[(1523.4±128.7)mgand(1567.9±141.2) mg](P>0.05).The anesthesia indexes and the incidence of adverse reactions of the two groups were similar(P>0.05).During the operation(T2、T3),the ET level[(133.5±19.6)pg/mland(130.4±22.0)pg/ml、(131.2±18.7)pg/mland(122.7±17.9)pg/ml,respectly] of both groups decreased,and the CGRP level[(60.4±7.8)pg/mland(63.1±8.1)pg/ml、(61.3±8.1)pg/mland(63.6±10.2)pg/ml,respectly] increased(P＜0.05);compared to that of group L,the ET level of group M was significantly lower and CGRP level was higher(P＜0.05).alanine aminotransferase(ALT) and Aspartate aminotransferase(AST) levels of two group were significantly increased after operation[(32.5±5.1)U/Land(29.0±5.3)U/L、(35.9±6.8)U/Land(32.7±6.5)U/L,respectly]compared to that of pre-operation(P＜0.05),there was no difference in two group(P>0.05).Triglyceride[TG,(1.8±0.3)mmol/L]and low-density lipoprotein[(LDL,(2.8±0.8)mmol/L]levels of group L were significantly increased(P＜0.05) after operation,and higher than that of group M [(1.4±0.7)mmol/Land(2.6±0.8)mmol/L](P＜0.05).
Conclusion Different dosage forms of propofol have similar anesthetic effects on patients with rectal cancer undergoing laparoscopic surgery,and can play a protectiverole of endothelial function by reducing ET and increasing CGRP levels,protective effection of M groupis better,there were hyper-triglyceride and hyper- low-density lipoprotein in L group.

Objective To investigate the effect of different nerve blocks on the prognosis of patients with pulmonary nodule undergoing video-assisted thoracic surgery.
Methods The clinical data of patients with pulmonary nodule undergoing video assisted thoracic surgery from June to December 2020 in Union Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology were reviewed.The relationship between different nerve blocks and the prognosis of patients were studied.
Results The postoperative hospitalization time of patients with nerve block(3(2,7) days) was significantly shortened compared with patients without nerve block[5(3,9)days，P＜0.05].Time spending in postanesthesia care unit for patients with preoperative nerve block(46(35,58) min) was significantly shorter than patients with postoperative nerve block[59(47,73) min)，P＜0.05],however there was no difference in postoperative hospitalization time between the two groups.There was also no significant difference in postoperative hospitalization time among patients with various types of nerve blocks(P＞0.05).
Conclusion Nerve blocks can significantly shorten the hospitalization time of patients with pulmonary nodule undergoing video assisted thoracic surgery and accelerate the postoperative rehabilitation of patients.

Objective To summarize and analyze the long-term efficacy of laparoscopic treatment of children with hiatal hernia.
Methods The data of 49 consecutive cases of pediatric hiatal hernia treated by laparoscopy in our hospital from January 2014 to December 2018 were retrospectively analyzed,with an age range of 2 to 85 months and a median of 18.5 months(P25 to P75,12.3 to 28.8 months).There were 1 cases of sliding hernia,17 cases of paraesophageal hernia and 31 cases of mixed hernia.Laparoscopic hiatal hernia repair and antireflux surgery were performed using a 4-well method.The operative time,intraoperative blood loss,recovery time of gastrointestinal function,postoperative hospital stay and postoperative complications were recorded,and the postoperative recovery was observed.
Results 3 cases were converted to open surgery,and the remaining 46 cases underwent laparoscopic surgery successfully.Postoperative follow-up ranged from 27 to 83 months,with a median of 64.0 months(P25 to P75,47.3 to 73.8 months).One patient with esophageal stenosis was significantly relieved after balloon dilation of esophageal stenosis.9 cases of gastroesophageal reflux,5 cases of drug antiacid treatment;One case of hiatal hernia recurred and was re-operated.
Conclusion The majority of children's hiatal hernia can be treated by laparoscopy,the operation is safe and feasible,the incidence of postoperative complications and recurrence rate is low,and the long-term treatment effect is satisfactory.

Pancreatic cancer is a kind of digestive system malignant tumor with late clinical discovery, high degree of malignancy and poor prognosis. In order to improve the prognosis of patients, it is of great clinical significance to explore an economical, accurate and minimally invasive method for early diagnosis and improve the resection rate of surgery.Liquid biopsies are used to detect a variety of tumor-related biomarkers, such as circulating tumor cells, circulating tumor DNA, and exosomes, in extractable body fluid samples. Recent studies have shown that liquid biopsy plays an important role in early diagnosis of pancreatic cancer. In this paper, the advantages, limitations and clinical application prospects of liquid biopsy-related markers in early diagnosis of pancreatic cancer were reviewed.

Recently,plenty of literature reported that pancreaticobiliary maljunction(PBM) was associated with biliary malignancies.With the deepening of the research,it has been found that pancreaticobiliary reflux also occurs in patients with normal pancreaticobiliary junction(occult pancreaticobiliary reflux,OPR).There are few reports on the correlation between OPR and biliary diseases up to now.The incidence of OPR is still not clear,and the clinical manifestation of OPR in the early stage is not characteristic.OPR cannot be diagnosed by routine imaging examination.However,some studies have shown that OPR was associated with a variety of biliary diseases and play a role in the development of gallbladder cancer.So related disciplines should attach importance to OPR.In this paper,we review the progress in the research of OPR.

Pancreatic cancer is a highly malignant disease in the digestive system.So far,surgical resection is still the primary treatment for pancreatic cancer,but only about 20% of pancreatic cancer patients can be treated with surgery.Even with comprehensive treatment measures such as surgery,radiotherapy and chemotherapy,biological therapy,and targeted therapy,the overall survival rate of pancreatic cancer patients has not been significantly improved in the past ten years.In recent years,immunotherapy has made breakthroughs in tumor treatment.Cancer immunotherapy has now been recognized as the fourth pillar of cancer treatment alongside surgery,radiotherapy,and chemotherapy.There are also many studies in the treatment of pancreatic cancer,but the results are not satisfactory.This article reviews the current status and possible prospects of immunotherapy for pancreatic cancer.

Colorectal cancer is one of the common gastrointestinal malignancies.The concept ofEnhanced Recovery after Surgery(ERAS) has been widely used in the perioperative treatment of colorectal cancer.Standardized nutritional support therapy can improve the nutritional status of patients,improve the tolerance of surgical treatment,and reduce the incidence of perioperative complications.Perioperative nutritional support has become an important part of ERAS.Its rational and individualized application can improve the treatment effect,survival rate and quality of life.