Abstract: Objective To investigate the effect of laparoscopic Roux-en-Y gastric bypass surgery (LRYGB) in the treatment of obese diabetes.Methods The clinical data of 20 obese diabetic patients who received LRYGB from 2012 to 2018 in the Minimally Invasive and Herniac Abdominal Surgery Center of Xinjiang People’s Hospital were retrospectively analyzed.Result The all 20 surgeries were successfully completed,and 1 case was converted to open surgery.The surgical time ranged from 60 to 420 minutes, with an average of (150±105.64) minutes,the intraoperative blood loss ranged from 20 to 100, with an average of (37.5 ± 20.99) ml,and the postoperative hospital stay ranged from 5 to 15, with an average of (8.25 ± 2.51) days.Complications occurred in 7 cases (35.00%) within 5 years after surgery,all of which were Clavien Dindo grade Ⅱ.The body weight,BMI,glycosylated blood glucose,fasting blood glucose,and the percentage of total weight loss (TWL%) at 1,3,and 5 postoperatively improved compared with those before surgery (P＜0.05).15 cases (75.00%) of type 2 diabetes were completely relieved by LRYGB 5 years after operation.Conclusion Laparoscopic gastric bypass surgery is an effective way to reduce weight and blood sugar in obese patients with type 2 diabetes.

Key words: laparoscopic Roux-en-Y gastric bypass, obesity, type 2 diabetes mellitus, bariatric surgery, laparoscopic sleeve gastrectomy