Abstract: Objective Explore the effect of percutaneous minimally invasive locking plate internal fixation combined with intra-articular injection of sodium hyaluronate on the postoperative comprehensive stress state of tibial plateau comminuted fractures.Methods A prospective study was conducted on 84 patients with tibial plateau comminuted fractures from June 2020 to June 2021.They were randomly divided into a minimally invasive group and a combination group,with 42 patients in each group.The minimally invasive group underwent percutaneous minimally invasive locking plate internal fixation(group A),while the combined group received intra-articular injection of sodium hyaluronate on the basis of the minimally invasive group(group B).Compare the efficacy of two groups of indicators.Results After 3 months of follow-up,the weight bearing time and healing time in the group B were significantly shorter than those in the group A (P＜0.05).The knee joint motion and Rasmussen score of group B at the 1st and 4th week after surgery were higher than those of group A, and the difference between the two groups was statistically significant (P＜0.05).The visual analogue scale (VAS) of the group B on the 3rd and 7th day after surgery was significantly lower than that of the group A (P＜0.05).On the 3rd and 7th day after surgery,the levels of interleukin-6 (IL-6),peripheral blood sedimentation rate (ESR),and serum C-reactive protein (CRP) in the group B were lower than those in the group A (P＜0.05).On the 3rd and 7th day after surgery,the levels of catalase (CAT),total antioxidant capacity (SOD),and superoxide dismutase (TAC) in the group B were higher than those in the group A (P＜0.05).Conclusion The combination of percutaneous minimally invasive locking plate internal fixation and intra-articular injection of sodium hyaluronate for the treatment of tibial plateau fractures has a good therapeutic effect.

Key words: crushed fracture of tibial plateau; internal fixation; steel plate; sodium hyaluronate; stress state