胃癌免疫治疗的临床研究进展

doi:10.3969/j.issn.1005-6483.2024.01.027

JOURNAL OF CLINICAL SURGERY ›› 2024, Vol. 32 ›› Issue (1): 99-102.doi: 10.3969/j.issn.1005-6483.2024.01.027

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Research and clinical progress of immunotherapy for gastric cancer

Department of Gastrointestinal Surgery ，Puren Hospital Affiliated to Wuhan University of Science and Technology，Wuhan University of Science and Technology，Wuhan 430081，China

Received:2023-02-10 Accepted:2023-02-10 Online:2024-01-20 Published:2024-01-20

Abstract

Abstract: 晚期胃癌治疗选择有限，易发生化疗耐药。目前，包括免疫检查点抑制剂、过继细胞疗法、肿瘤疫苗、非特异免疫增强剂及细胞因子疗法在内的免疫疗法对胃癌显示出了良好的疗效。载体药物及3D打印技术也在临床前实验中取得了疗效。临床试验采用免疫肿瘤学单一疗法或联合免疫化学疗法来提高胃癌病人的总体生存时间和客观反应率。根据初步证据，我们相信免疫治疗可以积极影响自然病史，改善胃癌病人的预后。

Key words: 胃癌, 免疫治疗, 免疫检查点抑制剂, 过继细胞疗法, 肿瘤疫苗

CLC Number:

gastric cancer

HUANG Tao, WANG Anxin, FU Guang. Research and clinical progress of immunotherapy for gastric cancer[J].JOURNAL OF CLINICAL SURGERY, 2024, 32(1): 99-102.