Abstract: Objective   To investigate the risk factors of persistent cough (cough after pulmonary resection,CAP) in patients with stage I lung cancer after thoracoscopic surgery.  Methods   The clinical data of 207 patients with stage I lung cancer who were admitted to the Department of Thoracic Surgery of Zhongnan Hospital of Wuhan University from January 2022 to January 2023 were retrospectively analyzed,including gender,age,length of hospital stay,smoking history,stage,left and right side of operation,and whether to dissect Lymph nodes around the trachea,pathological type,surgical method (lobe or segment),preoperative breathing training,etc.Univariate and multivariate Logistic regression were used to analyze the influencing factors of CAP.  Results   A total of 58 patients developed CAP after operation,the incidence rate was 28.01% (58/207).Univariate analysis showed that smoking duration,lymph node dissection around the bronchial tree,surgical method,and preoperative breathing training were associated with postoperative CAP (P<0.05).Multivariate analysis showed that smoking duration,lymph node dissection around the bronchial tree,and lobectomy were high risk factors for CAP(P<0.05).Preoperative breathing training was its protective factor(P<0.05).  Conclusion   The occurrence of CAP is related to the duration of smoking,the removal of lymph nodes around the bronchial tree,and the surgical method.Preoperative breathing training can effectively reduce the incidence of CAP.

Key words: lung cancer, thoracoscopy, cough after pulmonary resection, preoperative breathing training