Abstract: Objective To investigate the clinical efficacy of enhanced recovery after surgery(ERAS) combining with laparoscopy operation in gastric cancer and liver cirrhosis patients. Methods  From January in 2016 to December in 2020,46 patients of gastric cancer and liver cirrhosis were analyzed retrospectively，and divided into the conrtol group of 23 cases,perioperative management according to traditional methods,23 cases of accelerated recovery group(ERAS group),perioperative management with ERAS in Jingzhou central hospital.AST,ALT,d dimmers,White blood cell(WBC) count,C reaction protein(CRP) and IL-6 in the 46 patients were assayed preoperatively and at day 1,3,7 postoperatively.The operation time,intraoperative blood loss,pain scores,time to flatus,time to get out of bed,duration of hospital stay and postoperative complications were recorded and compared respectively. Results The leukocyte,C-reactive protein,interleukin-6,D- dimer and postoperative pain scores of ERAS group were significantly lower than those of control group at 1,3 and 7 days after surgery,and the differences were statistically significant(P＜0.05).The postoperative exhaust time,ambulation time and discharge time were all earlier than those of the control group,and the differences were statistically significant(P＜0.05).There was no significant difference in the incidence of postoperative alanine aminotransferase,aspartate aminotransferase and complications(P>0.05).Conclusion ERAS can decrease postoperative stress level,shorten the duration of hospital stay and postoperative complication for gastric cancer and liver cirrhosis.It is safe and feasible for the perioperative treatment of patients with gastric cancer and liver cirrhosis.

Key words: enhanced recovery after surgery, gastric neoplasms；liver cirrhosis