Abstract: To investigate the prognostic factors of primary hepatic angiosarcoma(PHA).
Methods We extracted 290 PHA cases between 1975 and 2016 from the Surveillance,Epidemiology and End Results database and performed survival analyses on the baseline characteristics.
Results Age≥70 years old,tumor size >85 mm,male,distant metastasis,no primary site surgery(PSS) and no chemotherapy were independent risk factors of PHA patients' prognosis(P<0.05).There was a survival difference between chemotherapy and no chemotherapy in patients who were distant metastasis with PSS,no metastasis without PSS,local metastasis without PSS and distant metastasis without PSS,respectively(P<0.05).
Conclusion PHA was rare with a poor prognosis and mainly occurred in elderly males.Early detection and diagnosis could improve survival rate.PSS and chemotherapy could improve prognosis,but patients who underwent PSS without distant metastasis might not benefit from chemotherapy.

Key words: hepatic angiosarcoma, treatment, prognosis, SEER database