Abstract: Objective：To investigate the management of immunosuppression in kidney transplant recipients with COVID19.Methods：Retrospective,five cases of kidney transplant recipients with confirmed COVID19;all the medical history,clinical features and the management of immunosuppression were recorded and analyzed.Results：The immunosuppression regimen was not adjusted in 1 common type patient.4 cases were severe/critical，while the mycophenolate mofetil was discontinued for (19.8±3.6)d in the other 4 severe/critical cases;tacrolimus was taken at half dosage for (8.3±4.1)d and complete discontinuation for (9.0±3.1)d due to uncontrolled symptoms.At the same time, 20~40mg/d methylprednisolone was given intravenously for (11.8±4.2)d.All the 5 patients had negative nucleic acid and normal renal function, and were discharged from hospital.The mean time from onset to discharge was (37.6±8.3) d.Conclusion：For kidney transplant patients with COVID19,especially those with severe pneumonia,reducing or withdrawal of immunosuppressive agents,as well as early lowdose and shortterm use of corticosteroids,are essential for good outcomes.

Key words: coronavirus disease 2019, kidney transplant, immunosuppressants, corticosteroids