Abstract: Objective：To explore the risk factors of preoperative hypoalbuminemia and the effects of hypoalbuminemia on complications after the primary hip arthroplasty.Methods：A total of 152 elderly hospitalized patients who underwent hip arthroplasty in the Zhongnan Hospital of Wuhan University from January 2019 to October 2019 were collected. All patients were divided into control group (serum albumin ≥ 35g/L,100 cases) and case group (serum albumin < 35g/L,52 cases). The perioperative conditions of the two groups of patients were recorded and compared. The relevant risk factors of preoperative hypoalbuminemia and the relationship between preoperative hypoalbuminemia and postoperative complications were analyzed.Result：Compared to the control group, the patients in the case group were older, had lower BMI, more likely fracture patients, had longer lengths of stay, the American Society of Anesthesiologists (ASA) scores and cardiac function scores were higher.Compared to controls, hypoalbuminemia patients had higher risk for any complications. There were no significant differences in surgical methods, anesthesia methods, intraoperative time, and intraoperative blood loss between the two groups.Conclusion：Patients who were older and have more comorbidities are more likely to have preoperative hypoalbuminemia.Preoperative hypoalbuminemia is associated with an increased incidence of various postoperative complications. The findings in the present study indicate the need to develop better pre and postoperative medical and nutritional care for primary hip arthroplasty patients in order to potentially mitigate their increased risk.

Key words: hypoalbuminemia, hip arthroplasty, risk factors, postoperative complications