Abstract: Objective To investigate clinical value of ultrasound-guided Mammotome（MMT）in the treatment of breast cancer.
Methods The clinical data of 75 patients with MMT and reoperation were collectedin the treatment of breast cancer.According to whether there was residual tumor after MMT，patients were divided into residual tumor group（39 cases）and non-residual group（36 cases）.The relationship of residual tumorsand clinical and pathological factors between two groups was compared.
Results The rate of residuallesions after MMT was 52.0%，The residual lesionswere closely related to patient age，tumor differentiation，Ki-67expression（P＜0.05）;patient age was an independent risk factor for residual breast tumor（P<0.05）.
Conclusion There was a high rate of residual tumors after MMT in breast cancer.MMT is not recommended for breast cancer.

Key words: breast cancer, Mammotome（MMT）, residual tumor