Abstract: Objective：To explore the application value of biodegradable material polyglycolic acid gasket（NEOVEIL）in thoracoscopic radical resection of esophageal cancer.Methods：A total of 301 patients with thoracoscopic resection of esophageal carcinoma in our hospital were collected，among which 206 were in the NEOVEIL group and 95 were in the routine group.The operative indicators，postoperative pathology and postoperative complications of the two groups were compared and analyzed.Results：There was no significant difference in general clinical data and postoperative pathology between the two groups.There was no statistically significant difference in the incidence of anastomotic fistula complications between the NEOVEIL group and the conventional group（11.2% vs.13.7%，P=0.531），but there was an advantage in the prevention of esophagotracheal fistula complications（0.5% vs.7.4%）（P<0.05）.Conclusion：In the radical resection of esophageal cancer，NEOVEIL gaskets have no obvious advantage in preventing the occurrence of esophageal anastomotic fistula，but they play a significant role in preventing esophagotracheal fistula after the occurrence of anastomotic fistula.

Key words: esophageal carcinoma, radical surgery for esophageal carcinoma, NEOVEIL gaskets, anastomotic fistula, tracheoesophageal fistula