Abstract: Due to the sharp increase of COVID19 infected cases，infectious specialized hospitals with negative pressure operating rooms have been unable to satisfy the needs of COVID19 surgical patients，and it is inevitable for general hospitals to make surgical treatment of suspected or confirmed emergency COVID19 patients.Therefore，it is urgent to implement the practice in the operating room at the stage of prevention and control of COVID19.During this period，the isolated operation area should be selected and transformed to meet the requirements of the three areas and two channels.The emergency training and assessment of the whole surgical team members（surgeons，anesthesiologists，surgical nurses，auxiliary staff）can not only provide mutual protection，but also avoid the waste of protective supplies，prevent the spread of infection and more shortage of protection materials.Emergency deployment，storage and management of protective supplies are to ensure clinical requirements.Rapid development of human resources plans，care of staff（especially nurses who support fever clinic，ICU and compartment hospital）quickly respond to the human support in and out of OR.Revision and sharing of surgical procedures and emergency plans，so that the whole team members know how to prevent from infection and compliant.Strengthen the communication with the medical aid teams for Hubei province to better deal with the emergency operation service for them.In the process of the practice，we realize the skills training with the infection prevention and control measures for medical staff is the biggest difficulty and challenges，reasonable human resource deployment and humanistic care and knowledge reserves are the key points to eliminate panic among employees，multidisciplinary collaborative discussion is to guarantee the area reconstruction and process revision，orderly grouping responsibility system is the driving force to carry out the practice efficiently.

Key words: coronavirus disease 2019, 〓infection prevention and control, 〓operating room, 〓management, 〓strategy