Abstract: Objective:To compare the prognosis of acute kidney injury and the absence of acute kidney injury with Stanford type A aortic dissection，and to analyze the high risk factors leading to acute kidney injury after surgery.Methods:From May 2014 to May 2016，75 patients with acute kidney injury after Stanford type A dissection were treated as a case group.Age and body weight were matched in 75 normal renal function groups as control group.The risk factors for acute kidney injury were analyzed.The prognosis of the two groups was compared.Results:The incidence of early complications of patients with acute kidney injury after Stanford type A aortic dissection increased about 1.9 times，and the rate of lung infection increased about 1.7 times compared with those who without.After 3 years of followup，the followup rate was 97.0% ，and the average followup was 28 months.The survival rate freedom from longterm complications decreased from 1 month，12 months，24 months，and 36 months after acute kidney injury compared with those who did not（94.2%，91.2%，80.5% and 26.4% vs.100%，98.6%，91.5% and 77.8%； Logrank P<0.01）.The perioperative highdose positiveinotropicdrugs（OR=3.455；95%CI：1.163～10.265）and static renal vascular damage（OR= 8.726；95%CI：2.149～35.426） were risk factors for acute kidney injury after Stanford type A dissection.Conclusion:Stanford type A aortic dissection surgery is dangerous，perioperative highdose positiveinotropicdrugs and static renal vascular damagewere risk factors for acute kidney injury after suregy.Those patients have a poor prognosis.Prevention is better than cure.

Key words: aortic dissection, acute kidney injury, prognosis, high risk factor