Abstract: Objective To review and analyze the clinical application of “tibiofibular line” in the injury of tibiofibular syndesmosis. Methods From June 2017 to July 2019，we used the concept of “tibiofibular line” to judge 45 patients with ankle injury，and successfully screened 32 patients with injury of tibiofibular syndesmosis. Results 32 patients were followed up for 10～22 months，with an average of 16 months，fracture healing time was 6～10 months with an average of 7 months. Conclusion “Tibiofibular suture”plays an important role in the diagnosis of lower tibiofibular syndesmosis injury，which can significantly reduce the misdiagnosis rate and missed diagnosis rate of lower tibiofibular syndesmosis injury，It can provide another accurate diagnosis method for the injury of tibiofibular syndesmosis.

Key words: “tibiofibular line”, tibiofibular syndesmosis, clinical application