Abstract: Objective To explore the therapeutic effect of lung transplantation for end-stage lung diseases，and to summarize the experience of perioperative treatment of lung transplantation. Methods The perioperative period clinical data of 13 cases of lung transplantation between December 2016 and September 2019 were analyzed retrospectively. Results The main diagnosis was chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis in 4 cases，respectively，and bronchiectasis in 3 cases.There was 1 case of pneumoconiosis and 1 case of Kartagener syndrome.7 cases underwent bilateral lung transplantation，3 cases received left unilateral lung transplantation and 3 cases received right unilateral lung transplantation.There were 3 deaths during perioperative period.The cause of death was Acinetobacter Baumannii combined with Pseudomonas Aeruginosa infection in 1 case，Klebsiella Pneumoniae infection in 1 case，and 1 case was dead of cardiac arrest.The remaining 10 cases were cured and discharged. Conclusion Lung transplantation is an effective method for the treatment of end-stage lung diseases.The emergency salvage surgery has little effect.

Key words: lung transplantation, perioperative period