Abstract: Objective：To explore the risk factors and preventive measures of periprosthetic femur fracture（PFF） after hip replacement.Methods：We retrospectively analysed 150 cases of hip replacement.Logistics regression was carried out to analyse the correlation between the preoperative，intraoperative and postoperative parameters and PFF.Results：130 of the 150 patients finished the followup and the followup rate was 90.0%.The average followup time was 31.2 months（25.3 to 42.5 months）.In the 135 cases of patients who finished the followed up，15 cases（11.1%）had PFF，and 120 cases（88.9%）had no PFF.Logistic regression analysis showed that age and type of prosthesis（biologic type）were the risk factors of PFF after hip replacement.The ROC（receiver operating characteristic）curve showed that area under curve（AUC 0.82）and biological prosthesis（AUC 0.80）owned good predictability for PFF after hip arthroplasty.Conclusion:Age and type of prosthesis（biologic type）were the risk factors of PFF after hip replacement，and special attention should be paid in the clinics.

Key words: periprosthetic femur fracture, risk factors, logistics regression, biological prosthesis, age