Abstract: [Abstract]〓Objective〖WTBZ〗〓To analyze differences in clinical efficacy of central pancreatectomy（CP）and distal pancreatectomy（DP）in the treatment of benign or borderline tumors of the pancreas.〖WTHZ〗Method〖WTBZ〗〓A retrospective study was used to analyze 39 cases of central pancreatectomy（CP group）and 52 cases of distal pancreatectomy（DP group）.The basic clinical features，intraoperative condition，postoperative complications and follow-up of the patients were observed.〖WTHZ〗Result〖WTBZ〗〓In the CP group，the operation time[（220.96±90.69）min] and diet start time[（4.29±1.05）d] were significantly longer than DP group[（275.52±88.78）min and（5.28±2.22）d]（P＜0.05）.There was no significant difference in serious complications including clinically significant pancreatic fistula（B+C），delayed gastric emptying，reoperative，and mortality（P＞0.05）.Compared with DP group，CP group patients could benefit from longterm postoperative exocrine and endocrine function（P＜0.05）.〖WTHZ〗Conclusion〖WTBZ〗〓These findings provide a rationale for CP could as an acceptable and reliable procedure，especially in improving the quality of life of patients.