Abstract: Objective〖WTBZ〗〓To compare ligation and Hemolok in securing of appendix stump in laparoscopic  appendectomy.〖WTHZ〗Methods〖WTBZ〗〓There were 105 patients undergoing  laparoscopic appendectomy.They were treated by two different methods in securing of the base of the appendix：silk ligation of the stump was performed in 53 cases（ligation group）； while stump ligation by using Hemolok clips was performed in 52 cases（Hemlock group）.Two groups were compared in operation time and postoperative patient recovery.〖WTHZ〗Results〖WTBZ〗〓Between the both groups，postoperative complications and postoperative hospital stay had no significant differences（P>0.05）.The operation time of the ligation group was （55.5±7.8）min，which was significantly longer than that of the Hemolok group[（46.1±5.6）min，（P<0.05）].The cost of appendix root treatment in the ligation group was 0.3 yuan，while the cost in Hemolok group was 560 yuan.The difference between the two groups was statistically significant（P<0.05）.〖WTHZ〗Conclusion〖WTBZ〗〓Both methods are safe and effective in securing of the base of the appendix in laparoscopic appendectomy.Pursestring suture is more in line with traditional appendectomy requirements and cost effective，but requiring more skilled laparoscopic manipulation.Hemolok clipping of the appendix saves operation time and is easy to perform，which is more suitable for beginners.