Abstract: Objective To investigate the effect of narrow-band imaging combined with endoscopic submucosal dissection in the treatment of lateral developmental tumors (LST) of the large intestine and the analysis of postoperative recurrence.Method 78 LST patients admitted to Changzhou Traditional Chinese Medicine Hospital between April 2019 and April 2022 were retrospectively selected,and the surgical methods were selected according to the patients' wishes.According to the surgical methods,they were divided into observation group (narrowband imaging combined with endoscopic submucosal dissection,n=39) and control group (endoscopic submucosal dissection,n=39).The perioperative period and postoperative recovery,tumor resection,postoperative complications and quality of life were compared.Result The operation time of the observation group was (68.16±10.13) minutes, the recovery time of defecation was (51.34±6.36) hours, the exhaust time was (47.28±10.78) hours, and the recovery time of bowel sound was (32.67±6.02) hours.In the control group, they were (76.03±10.11) minutes, (54.55±6.27) hours, (52.56±11.55) hours and (35.84±5.97) hours, respectively, and there was statistical significance between the two groups (P<0.05).The overall resection rate of observation group (39 cases /39 cases) was higher than that of control group (32 cases /39 cases), and the difference was statistically significant (P<0.05). The total rate of intestinal infection, dyspepsia and adverse reactions in observation group (5 cases /39 cases) was lower than that in control group (18 cases /39 cases), with statistical significance (P<0.05).The mental health scores of the observation group were (76.16±12.13), emotional function scores were (77.32±11.13), social function scores were (80.37±11.13),vitality score was (81.23±9.07), body pain score was (83.15±8.15),the physiological function score was (82.09±10.28) and the physiological function score was (85.27±8.28).the scores of control group were (62.34±11.09),(65.50±12.13),(72.18±10.07),(75.10±9.11),(76.11±7.07),(76.11±7.07) and (75.14±8.32), respectively.There was statistical significance between the two groups (P<0.05).Conclusion The combination of narrowband imaging technology and endoscopic submucosal dissection has a good therapeutic effect on laterally spreading tumor,with fewer postoperative complications.

Key words: narrowband imaging；intestinal endoscopy；submucosal dissection；colorectal cancer；laterally spreading tumor