Abstract: Objective To study the correlation between posterior urethral dilation and the severity and prognosis of posterior urethral valvular disease. Methods A total of 80 children with posterior urethral valve disease who were admitted to the pediatric surgery department of our hospital from January 2018 to December 2020 were selected.All the children underwent voiding cystourethrogram VCUG to measure the width of the urethra,and underwent transurethral cystoscopy for urethral valve electrotomy.Clinical data,urination,urine flow rate,residual urine,urinary tract infection,bladder morphology,hydronephrosis of kidney and ureter,vesicoureteral reflux,and renal function were compared between the two groups.Multivariate Logistic regression was used to analyze the correlation factors of postoperative prognosis of urethral valvular disease. Results Among the 80 patients included in the study,6 cases fell off,29 cases had poor prognosis and dysuria after operation,and were divided into the poor group,and the remaining 45 cases were divided into the control group,with the incidence of poor prognosis being 39.19%.The proportion of urethral dilatation length,urethral dilatation width,bladder wall thickening and trabecular hyperplasia and bladder dysfunction in the adverse group were higher than those in the control group(P＜0.05).Multivariate Logistic regression analysis showed that urethral dilation length(OR=8.880),urethral dilation width(OR=9.410),bladder wall thickening and trabecular hyperplasia(OR=5.375) were independent risk factors for the prognosis of posterior urethral valvular disease. Conclusion The length and width of urethral dilation,thickening of bladder wall and trabecular hyperplasia are the risk factors affecting the prognosis of urethral valvular disease.Early monitoring is helpful to understand the severity of urethral valvular disease and adjust the treatment plan.

Key words: posterior urethral valve disease, degree of posterior urethral dilation, excretory cystography and urethrography, prognosis