Abstract: Objective Summarize the clinical characteristics of gastrointestinal tract schwannoma.
Methods Using schwannoma as the search term,the clinical case reports of gastrointestinal tract schwannomas published in the CNKI database,Wanfang database,and Pubmed database during 2018-2020 were searched,and statistics and summary were made.
Results The 81 patients with gastrointestinal tract schwannoma were mostly female,aged between 31-84 years old and most of them occur in the stomach.The diameter of the tumor was between 0.2-9 cm.The clinical manifestations were mostly abdominal pain and bloating as the first symptoms,but most patients had no obvious symptoms.The accuracy of preoperative diagnosis was only 8.6%.All patients showed positive s-100 immunohistochemical expression after surgery.Complete resection of the mass or partial gastric (colorectal) resection was the main surgical method,and there was no recurrence or metastasis after surgery.
Conclusion Gastrointestinal  tract schwannoma is a benign tumor that is rare in the gastrointestinal tract.It has a high preoperative misdiagnosis rate.S-100 positive is the gold standard for diagnosis;surgical treatment is the main method,and the prognosis is rarely recurrence and metastasis.

Key words: gastrointestinal tract schwannoma, endoscopic ultrasonography, S-100, misdiagnosis