Abstract: Objective  To evaluate the outcome of the one-stage and two-stage implant-based breast reconstruction(IBBR) in terms of postoperative complications and patient satisfaction.
Methods  Clinical datawere retrospectively collected for patients who underwent one-stage and two-stage IBBR from 2013 to 2017.Postoperative complications,reoperations and patients' satisfaction were compared between the two groups.
Results  Biological patch resulted an increased risk of poor healing wound(OR:4.40,95%CI:1.27-15.29,P=0.02) and seroma(OR:9.30,95%CI:1.60-53.93,P=0.01).Radiotherapy resulted an increased risk of capsular contracture(OR:0.12,95%CI:0.03-0.49,P=0.003).The above complications appeared to be independent of operation mode.Two-stage IBBR only had more satisfactory aesthetic outcomes compared to one-stage IBBR(P<0.001),with no difference in complications and reoperations.
Conclusion  Both one-stage and two-stage IBBR could satisfy tumor safety and cosmetic effect.We recommend that the choice of techniquesshould be considered on a case-by-case basis.

Key words: breast cancer, one stage, two stage, implant-based breast reconstruction