Abstract: Objective：Analyze the composition and clinical characteristics of urinary calculi in Tibetan Plateau area.
Methods：This retrospective analysis explored the composition and clinical characteristics in 129 patients with urolithiasis,who were admitted to Lhasa People's Hospital and surrounding hospitals in Tibet Plateau area,from January 2018 to January 2019.
Results：Of the 129 cases of urolithiasis,78(60.5%) were males and 51(39.5%) were females.The ratio of males to females was 1.5∶1.The average age of the patients was(27.91±13.77)years old.92(71.3%) patients lived in farming or pastoral areas,while 37(28.7%) patients lived in cities.All cases drank water less than 2 000 ml every day.In terms of stone composition,the most common was calcium oxalate stone.47 cases(36.43%) were infection stones while 82 cases(63.57%) were noninfection stones.The incidence of infection stones in women(24 cases,47.06%) was significantly higher than men(23 cases,29.49%)(P＜0.05).
Conclusion：The ratio of infection stones in Tibetan Plateau was significantly higher than flatland areas in China,and this ratio in females was significantly higher than males.The average age of the patients suffered from urinary calculi was younger than other areas.The incidence of calculi was high in children and adolescents.All of these characteristics may be closely related to the specific local environment,climate and dietary habits.

Key words: urinary calculi, stone composition, Tibetan Plateau