Abstract: Objective To investigate the effect of breast mass biopsy on the accuracy of sentinel lymph node biopsy in breast cancer.
Methods Open biopsy and hollow needle biopsy were performed in 107 cases and 122 cases respectively.During the operation,fluorescent detector and methylene blue double tracer were used for sentinel lymph node biopsy.According to the proportion of blue staining sentinel lymph nodes,the difference of accuracy of sentinel lymph node biopsy was calculated by the incision position.
Results Multivariate regression analysis showed that the accuracy of SLN biopsy was significantly affected by the length and location of the incision and breast biopsy method(P<0.05).The results of multivariate analysis showed that there was significant difference between the open biopsy and hollow needle biopsy(P<0.05).
Conclusion The accuracy of sentinel lymph node biopsy was affected by the way of breast biopsy,the position and size of incision.

Key words: breast cancer, sentinel lymph node, fluorescence detector, biopsy, methylene blue