Abstract: Objective In order to investigate the clinical effect of simultaneous ureteral soft-scopy surgery on bilateral 2～3 cm upper ureteral stones，and to provide a reference for clinical treatment options，this study retrospectively analyzed 84 cases with bilateral 2-3 cm upper ureteral stones in our hospital from January 2016 to December 2018.The study subjects were divided into observation group（40 cases）and control group（44 cases）according to the surgical method.The observation group was treated with simultaneous ureteral soft endoscopic surgery，and the control group was treated with staged ureteral soft endoscopic surgery.The operation indexes，stone removal rate，medical expenses，level of inflammatory factors，urine routine，blood routine and complications of the two groups were compared.The total operation time，intraoperative hemorrhage，hospitalization time and medical expenses of the observation group were less than those of the control group（P<0.05）.The stone clearance rate of the observation group and the control group was 100.00% and 93.18%，respectively，with no significant difference（P>0.05）.The levels of TNF - α，IL-6，hs CRP，WBC and uroleukocyte in the two groups were significantly higher than those before operation（P<0.05），but there was no significant difference in the levels of TNF - α，IL-6，hs CRP，WBC and uroleukocyte between the two groups（P>0.05）.The total postoperative complication rate in the observation group（7.50%）was significantly lower than that in the control group（25.00%），and the difference was statistically significant（P<0.05）.
Conclusions indicate that simultaneous ureteral soft-scopy surgery has a significant effect on bilateral 2～3 cm upper ureteral stones.It can improve the clearance rate of primary stones and eliminate the need for secondary surgery.The length of hospital stay reduces the risk of complications.

Key words: upper ureteral stones; , soft ureteroscopy; , simultaneous surgery; , bilateral