Abstract: Objective:To observe the clinical effect of compound salvia tablet combined with magnesium sulfate in the treatment of epididymitis and the effect on the inflammatory factor levels in patient serum.Methods:120 cases were randomly divided into experimental group and control group.The control group was observed with levofloxacin hydrochloride injection for 21 days.In the experimental group，on the basis of the medication method of the control group，was treated with compound salvia tablet combined with magnesium sulfate for 21 days.The clinical effect in the experimental group and control group were observed.The levels of inflammatory factors of IL1β，IL6 TNFα and in patient serum of two groups were detected.Results:The effective rate 91.67% in the experimental group was obviously higher than that in the control group(80%).Before and after treatment，the pain scores in the control group were 10.57±0.05 and 5.30±0.11; the pain scores in the experimental group were 10.54±0.09 and 3.30±0.02; the QOL scores in the control group were 8.33±0.82 and 4.37±0.04; and the QOL scores in the experimental group were 8.57±0.03 and 3.26±0.03，with statistically significant differences (P<0.05).Compared with the control group，patients' pain scores and QOL in the experimental group were obviously decreased (P<0.05).After treatment，levels of inflammatory factor in the serum of the experimental group were （49.92±0.45）pg/ml，（8.94±0.16） pg/ml and（7.10±0.14）pg/ml，levels of inflammatory factor in the serum of the control group were （88.31±0.31）pg/ml，（18.25±0.26） pg/ml and（16.06±0.22）pg/ml，and the experimental group were better than the control group after treatment (P<0.05).Conclusion:Compound salvia tablet combined with magnesium sulfate can effectively treat epididymitis and reduce the level of inflammatory factors in patients' serum.

Key words: compound salvia tablets, magnesium sulfate, levofloxacin hydrochloride injection, epididymitis, clinical observation, inflammatory factors