Abstract:

Objective To study the Clinical efficacy and safety of ureteroscopic holmium: YAG laser lithotripsy in the treatment of upper urinary tract stones larger than 2cm.

Methods A total of 102 cases from January 2014 to January 2017 of upper urinary tract calculi treated with ureteroscopic holmium:YAG laser lithotripsy were included in the study.Analyze the clinical data of patients with age, sex, size, location,time of lithotripsy,stone removal and complications were retrospectively, and summarize the effectiveness and safety of operation.

Results  The mean cumulative maximum diameter of calculi is（28.56±20.45）min,the mean operative time is （44.18±20.45） min,the average hospitalization time is（7.2±2.4）days,the mean lithotripsy time is （28.56±20.45）min,and the mean length of hospitalization is （7.2±2.4）days.Complications occurred in 11 of 102 patients (10.78%), including fever,low back pain,hematuria,stone street and so on;There were no serious complications such as sepsis and septic shock.Multivariate regression analysis showed that hydronephrosis was the independent influencing factor of stone clearance rate and operative time was the risk factor for postoperative complications(P<0.05).

Conclusion The application of ureteroscopic holmium:YAG laser lithotripsy in the treatment of upper urinary tract calculi with clinical diameter larger than 2cm has high clinical safety.The rate of stone clearance is related to hydronephrosis, and the duration of operation is a risk factor for postoperative complications.

Key words: ureteroscopic holmium: YAG laser lithotripsy, upper urinary tract stones, safety