Abstract: Objective：To investigate the status of urinary tract infection and cellular inflammatory mechanism in elderly patients with prostate hyperplasia.ethods：A total of 186 elderly patients with benign prostatic hyperplasia admitted to our hospital from October 2016 to October 2019 by transurethral plasma resection of prostate were selected as the research objects,and the patients were divided into the infected group and the uninfected group according to the diagnostic criteria of clinical urinary tract infection.Postoperative inflammatory factors were compared between the two groups.To compare the general information of the two groups,multivariate Logistic regression was used to analyze the risk factors of urinary tract infection after BPH in the elderly.Results：Postoperative urinary tract infection occurred in 28 of 186 patients,with an incidence of 15.05%.The levels of monocyte chemokine 1(MCP1),fibroblast growth factor 2(FGF2),fibroblast growth factor 7(FGF7),tumor necrosis factor(TNF) and interleukin6(IL6) in the infected group were significantly higher than those in the noninfected group(P<0.05).Patients in the infected and uninfected groups were statistically significant in age,prostate size,preoperative preventive antibiotic use,urinary catheterization due to urinary retention,surgical time,postoperative indwelling catheter,total hospital stay,and diabetes(P<0.05).Twocategory multivariate Logistic regression analysis showed that preoperative urinary catheterization due to urinary retention,postoperative indwelling catheterization time ≥7 days,and diabetes mellitus were all independent risk factors(OR = 2.08,1.76,1.78,P<0.05).Conclusion：Patients with postoperative urinary tract infections have obvious cellular inflammatory reactions,postoperative urinary tract infections in elderly patients with benign prostatic hyperplasia are affected by a variety of factors,these include preoperative urethral catheterization due to urinary retention,prolonged indwelling catheter after operation,and diabetes.

Key words: elderly, prostatic hyperplasia, urinary tract infection, cell inflammatory mechanism