Abstract: Objective：This paper was to explore the value of combined examination of urinary bladder tumor antigen(BTA),urine exuviate cytology and urinary CT in the diagnosis of upper urinary tract urothelial carcinoma(UTUC).Methods：BTA test,Urinary exfoliative cytology and CT of the urinary system were performed on 51 patients who were suspected UTUC and admitted to our hospital from September 2018 to May 2020 were collected.Results：The sensitivity of urinary BTA(80.00%) and urinary CT(85.71%) was higher than that of urinary cytology(62.86%),but the specificity of urinary cytology(93.75%) was higher than that of urinary BTA(75.00%) and urinary CT(81.25%),and there were significant differences between each two groups(P<0.05).The sensitivity,negative predictive value and diagnostic coincidence rate of the combined tests were higher than those of each single test.And the BTA sensitivity increased along with the rise of pathological grade and stage of UTUC.Conclusion：BTA combined with exfoliative cytology and CT scan of urinary system improved the detection rate of UTUC and had high clinical value.

Key words: bladder tumor antigen, urinary cytology, urinary tract CT, upper urinary tract urothelial carcinoma