Abstract: Objective   To evaluate the clinical efficacy of posterior laminectomy in the treatment of intraspinal neurilemmoma. Methods  A total of 35 cases with intraspinal neurilemmoma was reviewed retrospectively in retrospective study.Of all cases，6 cases had defect in cervical spine，10 in thoracic，19 in lumbar of sacral.4 cases had dfect in intramedullary，21 in intradural extramedullary，10 cases in epidural and 8 cases were dumbbell shaped.All patients were treated with posterior laminectomy，of which 9 cases of nerve roots which can not be separated from the tumor were removed.Internal fixation was performed in 28 cases.Patients were followed up for the clinical effects.Xray and CT were performed to observe spinal stability and bone graft fusion.MRI were performed to observe the tumor recurrence. Results The tumors of  all 35 patients were completely resected，and all of them were neurilemmomas agter pathological examination.The operation time was 2～6 h，with an average of 3.6 h，and blood loss was 300～900 ml，with an average of 450 ml.After  the operation，1 case had sensory and motor dysfunction in the lower extremities，no obvious hematoma and spinal cord compression in MRI.The spinal cord ischemia reperfusion injury was considerd，and large dose of methylprednisolone was given in time，and the treatment of dehydration and nutrition nerve was given.The symptoms were improved obviously.The CSF leakage was found in 21 patients.The followup time was 3～34 months，with an average of 18.2 months.All the patients showed significant improvement in clinical symptoms and neurological function，and no recurrence occurred.No sponndylolisthesis and instability phenomena were observed in all 35 patients. Conclusion Posterior laminectomy can be effective in the  treatment of intraspinal neurilemmoma and can be better exposed and completely resected with microscope technique.
