Abstract: Objective    To investigate the causes and explore effective treatments of iatrogenic bile duct injury（IBDI）.Methods   Clinical data of 13 iatrogenic bile duct injury patients，who were analyzed to summarize the causes of bile duct injury and the experience of treatments.  Results  Among the 13 cases with IBID，2 cases were accessory right hepatic duct injury，7 cases were due to confused anatomic dissection of the gallbladder triangle，2 cases were caused by electric cauterization，common bile duct of 1 case was clamped due to excessive traction，and 1 injury was caused by adhesion and compression of biologic adhesive.For the treatments，4 patients received intermittent suture of bile duct plus T tube drainage，5 patients received bile duct endtoend anastomosis plus T tube drainage，and 4patients were treated by RouxenY biliaryenteric anastomosis.Except for one case of failure，the other 12 cases were successfully cured in the initial repair operation.Conclusion  IBDI was often caused by unclear anatomy and rough operation.Most of the lesions locate in the upper and middle part of the common bile duct.The RouxenY anastomosis is a safe and effective surgical procedure for IBID treatment.More importantly，prevention is the basic way to avoid IBID.

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