Abstract: With the increasing awareness of the adverse effects of long-acting opioids,opioid free anesthesia (OFA) is important in clinical practice.Regional block plays an important role in reducing perioperative opioids demands due to its analgesic effect.In this article,we review the application of regional block in neurosurgery,breast surgery,and thoracic surgery to explore the clinical progress of this kind of anesthetic technique.

Key words: regional block opioid free anesthesia；ultrasound guided block