Abstract: Objective To explore the effect of individualized lung rehabilitation training on rapid postoperative rehabilitation intervention in lobectomy patients with concomitant high-risk factors.Methods A total of 102 patients with high-risk factors undergoing pulmonary lobectomy admitted to our hospital from February 2021 to December 2022 were selected and divided into experimental group(51 cases) and control group(51 cases) by random number table method.The reference group received traditional standardized lung rehabilitation training,while the experimental group received individualized lung rehabilitation training.The clinical hospitalization time,chest tube removal time,lung function,motor function indicators,quality of life,and incidence of complications were compared between the two groups after intervention.Results After intervention,the hospitalization days[(10.34±2.06) d] and the chest tube removal time[(3.86±0.55)d] of the experimental group were significantly shorter than those of the control group[(13.23±2.21) d and (4.65±0.62)d](P<0.05)]; the forced vital capacity [FVC,(2.52±0.42)L],maximum air volume [MVV,(66.82±7.32)L] and 1s forced expiratory volume [FEV₁,(1.35±0.24)L] of experimental group were significantly higher than those of control group[（2.11±0.36）L,（62.02±6.59）L,（1.24±0.22）L](P<0.05); the FMA scores[(81.86±8.36)points] and 6min walking distance[(221.66±25.24)m] were significantly higher than those of control group [(72.43±7.51)points and (183.23±20.75)m](P<0.05); the SF-36 score of the experimental group[(85.36±9.11)points] was significantly higher than that of the control group[(79.43±8.68)points](P<0.05); the incidence of complications in the experimental group was obviously lower than that in the reference group(5.88% vs 21.57%,P<0.05).Conclusion Individualized lung rehabilitation intervention training can effectively improve lung ventilation function and exercise tolerance in lobectomy patients with concomitant high-risk factors.