Abstract: Objective To analyze the curative effect of suspended airless laparoscopic surgery on inguinal hernia in children.Methods 180 children with inguinal hernia who received treatment at the Fourth Affiliated Hospital of Guangzhou Medical University from June 2020 to February 2023 were selected.Random number table method was used to divide the patients into two groups, 90 cases in each group.The control group underwent laparoscopic high ligation of hernia sac,the observation group was treated with suspended airless laparoscopic surgery,and the clinical efficacy and surgical situation,postoperative pain and stress index levels,as well as the impact on testicular volume and quality of life,complications,and recurrence rate were compared between the two groups.Results There was no statistically significant difference in clinical efficacy between the two groups of children (P>0.05).The surgical performance of the observation group was better than that of the control group (P＜0.05).The scores of the simplified McGill pain questionnaire were (23.23±5.11) points and (25.51±5.21) points in the observation group and control group 12 hours after surgery, and (20.02±4.55) points and (22.73±4.46) points on the first day after surgery, respectively. 3 days after surgery, the scores were (11.76±1.71) points and (12.63±1.82) points, respectively, and the difference between the two groups was statistically significant (P < 0.05).On the second day after surgery,the elevated levels of stress indicators such as interleukin-6 (IL-6),interleukin-10 (IL-10),cortisol (Cor),and malondialdehyde (MDA) in the observation group were lower than those in the control group [（29.03±4.21）ng/L vs （30.86±4.15）ng/L,（30.12±4.23）ng/L vs （32.02±4.41）ng/L,(47.11±6.63)mmol/L vs (50.17±6.71)mmol/L,(24.31±5.18)μmol/L vs (26.63±5.25)μmol/L](all P＜0.05).There was no statistically significant difference in testicular volume between the two groups (P>0.05),while the quality of life score of the observation group was lower than that of the control group (P＜0.05).The incidence and recurrence rates of complications such as scrotal edema and inguinal pain in the observation group were not statistically significant compared to the control group (P>0.05),but the subcutaneous emphysema rate in the observation group was lower than that in the control group (P＜0.05).Conclusion Suspended gasless laparoscopic surgery and laparoscopic high ligation of hernia sac have good therapeutic effects in treating pediatric inguinal hernia,while the former has advantages in reducing postoperative pain and stress response.

Key words: suspended airless laparoscopic surgery; laparoscopic high ligation surgery; inguinal hernia in children; pain; stress response