Abstract: Methods  The information of 108 patients who was diagnosed with esophageal foreign body from January 2014 to June 2021 and accepted multiple-discipline cooperated diagnosis and treatment consisted of cardiothoracic surgery department,digestive system department,emergency department,imaging department and anesthesiology department was collected.Then,we compared the difference of clinic time,foreign body type,endoscopic findings,position of incarnation,complications,postoperative hospital stay between surgical treatment and medical treatment.Results Patients in medical treatment were older than surgical treatment [(59.21±13.12 ）years VS.(52.65±12.66)years,P＜0.05].Clinic time shew a skewed distribution,clinic time was longer in surgical treatment compared with medical treatment by rank sum test (P＜0.05).There were statistical differences in foreign body type,esophageal injury and complications between the two groups(P＜0.05).The white blood cell count of endoscopic treatment group and surgical treatment group was (7.89±3.08)×10⁹/L and(11.69±6.98)×10⁹/L,respectively(P<0.05),neutrophil counts were(6.16±2.96)×10⁹/L and(9.97±6.97)×10⁹/L,respectively(P<0.05),proportion of neutrophils were (76.11±8.75)% and(81.52±12.52)%,respectively(P<0.05), and C-reactive protein level were (43.26±56.87)mg/L and(111.37±102.86)mg/L,respectively(P<0.05).Conclusion Multiple-discipline cooperated diagnosis and treatment is safe,rapid and effective in the diagnosis and treatment of esophageal foreign bodies.Patients with longer clinic time,higher white blood cell counts,higher neutrophil counts,higher proportion of neutrophils,and higher C-reactive protein level were more likely to require surgical treatment.

Key words: esophageal foreign body, esophageal perforation, multi-disciplinary treatment