Abstract: Objective To investigate the efficacy of different Uncut Roux-en-y surgical approaches on patients with gastric cancer and the effect on their test indicators and prognosis.Methods 96 patients with distal gastric cancer admitted to our hospital from March 2018 to February 2021 received laparoscopic assisted radical gastrectomy for distal gastric cancer.According to surgical methods,96 patients were divided into 2 groups.Among them,46 patients in the study group were treated with modified U-RY anastomosis,while 50 patients in the control group were treated with U-RY anastomosis.Perioperative indicators (operation time,intraoperative blood loss,first ventilation time,hospital stay and drainage volume on the first day after operation),tumor-related indicators (CEA,CA199) before and after operation,postoperative complications and prognosis one year after operation were compared between the two groups.Results Except for the drainage volume on the first day after surgery, the other indexes (operation time, intraoperative blood loss, first ventilation time and hospital stay) of the study group were better than those of the control group（P<0.05）.The tumor-related indexes (CA199,CEA) were not different between the two groups before surgery (P>0.05),while the tumorrelated indexes (CA199,CEA) were lower in both groups after surgery compared with those before surgery (P<0.05);after surgery,the overall complication rate was lower in the study group than in the control group (8.7% vs.30.0%,P<0.05);one year after surgery,there was no difference in the survival and recurrence rates between the two groups (97.8% vs.96.0%;4.3% vs.6.0%;P>0.05).Conclusion The application of modified U-RY anastomosis in LADG significantly shortens the operative time of patients,accelerates their recovery,and reduces their postoperative complication rate,which ultimately does not affect their prognosis.

Key words: gastric cancer, laparoscopic-assisted radical resection of distal gastric cancer, uncut Roux-en-Y, efficacy, prognosis