JOURNAL OF CLINICAL SURGERY ›› 2022, Vol. 30 ›› Issue (12): 1196-1199.doi: 10.3969/j.issn.1005-6483.2022.12.028

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The research progress of exosome in the treatment of hypertrophic scar and keloid

  

  1. Department of Plastic and Aesthetic Surgery,Wuhan University People's Hospital,Wuhan 430060,China
  • Received:2022-11-20 Accepted:2022-11-20 Online:2022-12-20 Published:2023-01-20

Abstract: In the terminal stage of the human wound repair process,it is often accompanied by scar formation.Hypertrophic scar and keloid may occur when the orderly repair process of the body is broken and the wound heals abnormally.The emergence of them not only brings physical and mental burden to patients,but also consumes a lot of medical resources.Clinically,scar is mainly treated by surgery,local radiation and drug injection,but there is still a little gap between its curative effect and expectation.Therefore,it is of great significance to explore new treatment methods.Existing studies have shown that exosomes  have a certain therapeutic effect on scar.This review will summarize the mechanism and recent research progress of exosome in the treatment of hypertrophic scar and keloid.

Key words: exosome, hypertrophic scar, keloid, scar treatment

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