胶质瘤分子靶向治疗进展

doi:10.3969/j.issn.1005-6483.2022.10.028

JOURNAL OF CLINICAL SURGERY ›› 2022, Vol. 30 ›› Issue (10): 998-1000.doi: 10.3969/j.issn.1005-6483.2022.10.028

Department of Neurosurgery,Tongji Hospital,Tongji Medical College,Huazhong University of Science & Technology,Wuhan 430030,China

Received:2022-09-21 Revised:2022-09-21 Online:2022-10-20 Published:2022-10-20

Abstract

Abstract: Glioma is the most common intracranial malignant tumor,among which glioblastoma is the most malignant and still incurable.The main reasons for its recurrence include high heterogeneity of tumor,invasive growth,resistance to existing treatments,etc.Many genetic changes promote the occurrence and malignant progression of glioma.At present,great progress has been made in the molecular research of glioma.Individualized and precise treatment for genetic changes may be the hope of curing glioma in the future,but the results of many basic trials and clinical studies are still not ideal.In this article,based on relevant literature,we reviewed the progress of molecular research and targeted therapy of glioma.

Key words: glioma;molecular research;targeted therapy;progress ,

CHENG Lidong, LIU Jingdian, SHU Kai. Current status and progress of molecular research and targeted therapy for glioma[J].JOURNAL OF CLINICAL SURGERY, 2022, 30(10): 998-1000.

References

Metrics

Viewed

Full text

Abstract

Cited

Shared

Discussed

Comments

Recommended 9

[1]	ZHANG Lei, SUN Yu, HUANG Yi.. Comparison of postoperative sphincter fistula ligation and incision and suture for postoperative pain，anal function and wound healing time of sphincter anal fistula[J]. JOURNAL OF CLINICAL SURGERY, 2019, 27(6): 495 -497 .
[2]	WANG Bo, LIU Baoqing, MAO Zhangfan, et al.. Clinical correlation and expression of high mobility group box 1 protein and receptor of advanced glycation endproducts in patients with calcific aortic valve disease[J]. JOURNAL OF CLINICAL SURGERY, 2019, 27(10): 862 -865 .
[3]	CHEN Hong, DING Jie, WANG Meng, et al.. Expression of chemokine ligand 12/chemokine receptor 7 in gastric cancer and its correlation with clinicopathological features[J]. JOURNAL OF CLINICAL SURGERY, 2019, 27(10): 866 -869 .
[4]	. Analysis of the composition and clinical characteristics of urinary calculi in Tibetan Plateau area[J]. JOURNAL OF CLINICAL SURGERY, 2021, 29(2): 126 -128 .
[5]	LIU Kun, WU Heshui.. Current status and progress of immunotherapy for pancreatic cancer[J]. JOURNAL OF CLINICAL SURGERY, 2021, 29(7): 687 -690 .
[6]	ZHOU Wei, SHI Yuan, SHENG Qizhi, et al.. Effect analysis of patella steel plate and Kirschner wire tension band fixation in treating patella fracture[J]. JOURNAL OF CLINICAL SURGERY, 2021, 29(9): 864 -868 .
[7]	DU Jingcheng, HOU Guiting, LI Dan, et al. Comparison of different doses of dexamethasone combined with ropivacaine in intermuscular groove brachial plexus block[J]. JOURNAL OF CLINICAL SURGERY, 2022, 30(6): 528 -531 .
[8]	. [J]. JOURNAL OF CLINICAL SURGERY, 2022, 30(8): 705 -707 .
[9]	HUANG Ankang, GONG Yongsheng. Application and progress of small lung nodule localization technology in lung cancer surgery[J]. JOURNAL OF CLINICAL SURGERY, 2022, 30(8): 793 -796 .

Current status and progress of molecular research and targeted therapy for glioma

PDF (PC)

PDF (Mobile)

Abstract

Cite this article

share this article

References

Related Articles 2

Metrics

Comments

Recommended 9

[1]	LIU Mingxin, XU Jianjun. Analysis of causes and treatment of iatrogenic bile duct injury [J]. JOURNAL OF CLINICAL SURGERY, 2018, 26(10): 777-779.
[2]	LI Yong, LIU Yanxiong. A study of the efficacy and safety evaluation of proximal femoral nail anti rotation fixation for osteoporotic intertrochanteric fractures [J]. JOURNAL OF CLINICAL SURGERY, 2018, 26(10): 789-791.