Abstract: Objective To observe the analgesic effect and safety of ropivacaine and levobupivacaine in high ligation of hernia sac under ultrasonography guided transversus abdominis plane block.Methods A retrospective study was conducted on 133 children with inguinal hernia admitted to our hospital from March 2018 to March 2020.Nerve block drugs were divided into two groups:ropivacaine group(RP group) and levobupivacaine group(LB group),with 62 cases in RP group and 71 cases in LB group.Clinical indexes,analgesic effect(FLACC) and safety were compared.Results There were no significant differences in extubation time,recovery time and hospitalization time between the two groups(P>0.05),and the dosage of remifentanil in LB group was significantly lower than that in RP group(P<0.05).The FLACC score at T1 was significantly higher than that at T0,T2 and T3(P<0.05).The FLACC scores of LB group at T1 and T2 were significantly lower than those of RP group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The ultrasonic guided ropivacaine or levobupivacaine transversus abdominis plane block had good analgesic effect in the high ligation of children's hernia sac.The analgesic effect of levobupivacaine was stronger than that of ropivacaine,both are equally safe.

Key words: high ligation of hernia sac, transversus abdominis plane block, Ropivacaine, levobupivacaine, analgesic effect