Abstract: [Abstract] Objective To compare effects of ticagrelor/clopidogrel on bypass in patients with hypertension complicated with diabetes 1 year after CABG.Methods 78 patients undergoing CABG in our hospital from March 2016 to August 2020 were selected and divided into group A(clopidogrel) and group B(ticagrelor).CTA was performed 1 year after the operation to assess bypass,and adverse events were followed up.Results There were no significant differences in general data,total/arterial bridge vessel patency,angina and bleeding events between 2 groups(P>0.05).The patency of vein bypass in group B was significantly higher than group A(76.8%vs.89.2%,P=0.042).Logistic regression suggested that ticagrelor reduced the risk of bridging stenosis(OR=2.488,95%CI:1.016-6.091,P=0.046).〖WTHZ〗Conclusion 1 year after CABG,ticagrelor better maintained bridge patency in hypertensive patients with type 2 diabetes.

Key words: coronary artery bypass grafting, hypertension, type 2 diabetes mellitus, ticagrelor, clopidogrel