Abstract: Objective To investigate the Clavien-Dindo classification of complications after laparoscopic-assisted radical gastrectomy and the impact factors.Methods Clinical data of 478 patients with gastric cancer undergoing laparoscopic-assisted radical resection from January 2014 to June 2019 were analyzed retrospectively.The postoperative complications were assessed by Clavien-Dindo classification,and the impact factors associated with postoperative complications were assessed by using the Logistic regression model． Results Of the 478 patients,postoperative complications occurred in 84 patients(17.6%)．The Clavien-Dindo classification of postoperative complication：6 patients were detected in gradeⅠ,59 in gradeⅡ,11 in grade Ⅲa,4 in grade Ⅲb,3 in grade Ⅳa and 1 in grade Ⅴ,respectively.On univariate logistic analysis,postoperative complication was associated with age,BMI,preoperative comorbidity,surgical duration,intraoperative blood loss,tumor size and perioperative transfusion．Multivariate analysis revealed that age age≥65 years,BMI≥28kg/m²,surgical duration time>180min,intraoperative blood loss≥200ml and perioperative transfusion were independent risk factors for postoperative complications.The grades of Clavien-Dindo classification were significantly different between patients with different age,BMI,surgical duration,intraoperative blood loss and perioperative transfusion(all P＜0.05)．Conclusion Clavien-Dindo classification of complicationsis beneficial to the comprehensive evaluation of safety of laparoscopic-assisted radical gastrectomy.The mainly complications after laparoscopic-assisted radical gastrectomy are grade Ⅱ of Clavien-Dindo　classifification.Age,BMI,surgical duration,intraoperative blood loss and perioperative transfusion were independent risk factors for postoperative complications in laparoscopic-assisted radical gastrectomy.

Key words: stomach neoplasms, laparoscopic surgical procedures, Clavien-Dindo classification, postoperative complication