Abstract: Objective To investigate efficacy and safety of holmium laser enucleation of the prostate in the treatment of BPH with urinary retention(UR). Methods 198 patients with BPH were selected and divided into UR group(Sixty nine cases with UR) and non-UR group(129 cases without UR).Holmium laser enucleation of prostate was operated.The specimen quality,operation time,enucleation time,enucleation rate,postoperative urinary catheter indwelling time,bladder irrigation time,hospitalization time and hemoglobin change value were recorded.Postoperative complications were statistically analyzed.Patients were followed up for 1,3 and 6 months after operation,and their post-voiding residual(PVR),maximum urinary flow rate(Qmax),international prostatic symptom score(IPSS) and quality of life score(QoL) were recorded. Results The positive rates of urine white blood cells,urine culture and PVR in the UR group were higher than those in the non-UR group( P＜0.05).The PVR,IPSS and QoL of the two groups were decreased compared with those before operation,and the Qmax was increased compared with that before operation(P＜0.05).There was no significant difference in enucleation specimen quality,enucleation rate,indwelling time of urinary catheter,bladder irrigation time,hospitalization time,hemoglobin change value,incidence of complications,PVR,IPSS,QoL and Qmax between the two groups(P＞0.05).The PVR,IPSS and QoL of the two groups were decreased compared with those before operation,and the Qmax was increased compared with that before operation(P＜0.05).Conclusion Holmium laser enucleation of prostate is effective,safe and reliable in the treatment of BPH complicated with UR.

Key words: benign prostate hyperplasia, urinary retention, holmium laser enucleation of prostate, complications