Abstract: Objective To study the value of serum D-D combined with VEGF in predicting the risk of DVT after multiple rib fractures.
Methods Ninety two patients with multiple rib fractures in our hospital were selectedand divided into the occurrence group and the non-occurrence group according to whether DVT occurred.The differences in clinical data were compared.Logistic regression analysis method to analyze the influencing factors of DVT.ROC to analyze the value on the risk of DVT.
Results The ratio of age≥60 years old,history of diabetes,history of hypertension,and history of varicose veins,serum D-D and VEGF of the occurrence group were higher than those of the non-occurring group,of which the operation time was longer than that of the non-occurring group(P＜0.05).Logistic regression analysis showed that age≥60 years old,diabetes,operation time,serum D-D,VEGF were all influencing factors of DVT(P＜0.05).ROC results showed that the AUC of serum D-D and VEGF alone and combined to predict DVT were 0.741,0.705,0.796,respectively.
Conclusion Serum D-D combined with VEGF are highly effective in predicting the occurrence of DVT after multiple rib fractures.

Key words: deep vein thrombosis, d-dimer, vascular endothelial growth factor