Abstract: Objective To summarize the clinical features,diagnosis,treatment and prognosis of sarcomatoid carcinoma of the colon.
Methods The clinicopathological data of patients with sarcomatoid carcinoma of the colon in our hospital from January 1,2013 to September 1,2020 were retrospectively collected.
Results There were 1 male and 2 female patients with an average age of 62 years(52-72 years).Serum CA19-9 was elevated in 1 case.The images showed irregular thickening of the intestinal wall with enhancement.All 3 cases underwent curative resection,1 case underwent open surgery and 2 cases underwent laparoscopic surgery.Pathological examination showed that tumor was composed with low adhesion spindle tumor cells,which expressed CAM5.2,vimentin,INI1 and BRG1.One case had gallbladder invasion and one case had lymph node metastasis.At the end of follow-up,1 case died.
Conclusion Sarcomatoid carcinoma is a special subtype of colorectal cancer with poor biological behavior.The diagnosis should be combined with histomorphology and immunohistochemistry.Curative operation is an effective way to obtain good prognosis.

Key words: sarcomatoid carcinoma, intestinal cancer, spindle cell carcinoma, prognosis