Abstract: Objective：To explore the clinical effects of different viscosity bone cements in percutaneous kyphoplasty(PKP) on senile osteoporotic vertebral compression fractures(OVCF).Method：A total of 60 OVCF patients admitted to the hospital from May 2018 to October 2020 were selected as the research objects.According to different treatment methods,they were divided into a control group(28 cases) and an experimental group(32 cases).Patients in the control group were injected with lowviscosity bone cement during PKP,and patients in the experimental group were injected with highviscosity bone cement during PKP.Calculate relevant indicators during the perioperative period and compare the bone cement leakage between the two groups.The anterior edge height of the vertebral body and the Cobb angle of kyphosis were compared between the two groups of patients before and after the operation,and the recovery rate of the vertebral body height and the rate of kyphosis correction were calculated.Followed up for 3 months,Compare visual analog pain score(VAS),Oswestry dysfunction index(ODI),health survey summary(SF36) score.Result：All 60 patients were successfully operated.The average operation time was(28.25±5.24) min,and the average amount of bone cement was(2.58±0.35) ml,the total leakage rate of bone cement in the experimental group was lower than that in the control group(P＜0.05),and all patients had no nerve damage during the operatio.The compression height of the anterior edge of the vertebral body and the Cobb angle of kyphosis were significantly lower than that of the preoperative 7 days and 3 months after the operation(P<0.05),and the experimental group was significantly lower than the control group(P<0.05) on the 7th day after the operation.There was no statistical difference between the two groups in March(P>0.05).The postoperative vertebral body height recovery rate and kyphosis correction rate in the experimental group were higher than those in the control group(P<0.05).The VAS and ODI scores of the two groups were lower than that of the preoperative 7 days after operation(P＜0.05).There was no significant difference in the VAS and ODI scores between the groups(P＞0.05),the SF36 scores of the two groups were higher than those before the operation at 3 months after operation(P＜0.05),and there was no statistical difference between the groups(P＞0.05).Conclusion：The used of highviscosity and lowviscosity bone cement during PKP surgery in elderly OVCF patients has significant effects,and the two have the same effect on pain and lumbar function improvement,the highviscosity bone cement can better restore and correct the vertebral structure,and the cement leakage rate was low.

Key words: percutaneous kyphoplasty, bone cement, osteoporotic vertebral compression fracture