Abstract: Objective：To observe the therapeutic effects of all seeing needle percutaneous nephroscopy combined with flexible ureteroscopy for the treatment of parapelvic cysts.Methods：A total of 71 patients with parapelvic cyst admitted to our hospital from July 2014 to January 2019 were divided into experimental group and control group.Patients in the test group(n=35) received treatment with allseeing needle percutaneous nephroscopy combined with flexible ureteroscopy,and patients in the control group(n=36) received treatment with laparoscopic parapelvic cyst decortication.The therapeutic effects and complications were observed and compared between the two groups.Results：The duration of surgery of  the test group was(46.83±8.37)min,the bedridden days was(1.86±0.33)d,the days of hospital stay was(6.17±0.82)d,the treatment cost was(1.41±0.09)ten thousand yuan,and the rate of  hemorrhage and infection were both 2.86%.The duration of surgery of the control group was(47.86±6.78)min,the bedridden days was(1.94±0.39)d,the days of hospital stay was(5.86±0.87)d,the treatment cost was(1.37±0.08)ten thousand yuan,and the rate of hemorrhage and infection were both 5.56%.There was no significant difference between the two groups in the above indicators(P>0.05);the postoperative urinary leakage and cyst recurrence rates in the test group were 0 and 2.86%,respectively,which were significantly better than those of the control group(11.11% and 19.44%,P<0.05).Conclusion：Allseeing needle percutaneous nephroscopy combined with flexible ureteroscopy provides a minimally invasive,safe and effective treatment approach for parapelvic cysts.