Abstract: Objective To summarize and analyze the application value of vacuum sealing drainage combined with wound drainage and washing in refractory chest wall tuberculosis.
Methods From January 2015 to January 2020,75 patients with refractory chest wall tuberculosis were selected and analyzed retrospectively.According to the condition of skin defect,the surgical patients were divided into three groups:group A with stage Ⅰ suture drainage,group B with vacuum sealing drainage and wound washing,and group C with conventional tension reduction suture.The non-surgical patients were divided into vacuum sealing drainage(Group D) and wound washing(Group E) at the same time of anti tuberculosis and anti infection treatment.
Result Use time of anti infective Drugs:Group A was (18.611±1.787)days,Group B was (20.158±1.893)days,Group C was (27.571±3.006)days,the difference between the two groups was statistically significant(P<0.05);Group D was (21.455±3.045)days,Group E was (27.923±2.178)days,the difference between the two groups was statistically significant(P<0.05).Wound healing time:Group A was (17.167±6.662)days,Group B was (26.579±3.991)days,Group C was (36.786±5.102)days,the difference between the two groups was statistically significant(P<0.05).Group D was (29.273±7.072)days,Group E was (48.923±8.893)days,The difference between the two groups was statistically significant(P<0.05).VAS pain score 3 days before treatment:the score of group A was (2.361±0.637)，the score of group B was (2.648±0.853)，there was no significant difference(P>0.05)；the score of group B was (2.648±0.853)，the score of group C was (5.429±1.124)，the difference between the two groups was statistically significant(P<0.05).The score of group D was (3.455±1.293),the score of group E was (5.192±0.855),the difference between the two groups was statistically significant(P<0.05).
Conclusion In the treatment of refractory chest wall tuberculosis wounds,the application of negative pressure wound drainage combined with wound washing can speed up the healing process, reduce the use time of antibiotics and relieve the pain of patients.

Key words: refractory wound, tuberculosis of chest wall, vacuum sealing drainage, wound washing, rehabilitation