Abstract: In recent years,the number of overweight and obese people in China has increased significantly,which will increases the possibility of a series of chronic diseases.Domestic and foreign scholars have reported that obesity is related to the onset of hyperuricemia and obesity is one of the risk factors for hyperuricemia.Hyperuricemia is a major risk factor for symptomatic gout,which can lead to a variety of diseases,including gout,kidney damage,and arthritis.The mechanism of hyperuricemia in obese patients is very complicated.In addition,more and more clinicians advocate weight loss metabolic surgery for the treatment of obesity combined with hyperuricemia as a safe and effective treatment.In this paper,the mechanism of correlation between obesity and hyperuricemia and the progress of surgical treatment were reviewed for clinical reference.

Key words: obesity, hyperuricemia, xanthine oxidase, laparoscopic sleeve gastrectomy