Abstract: Objective：To explore the risk factors of recurrence of fractures in elderly patients with osteoporotic spinal fractures treated with minimally invasive surgery.Methods：Retrospective analysis was performed on the clinical data of 90 elderly patients with osteoporotic fracture treated with microsurgery in our hospital from January 2015 to June 2019.Logistic regression analysis was performed to analyze the independent risk factors for postoperative refracture in elderly patients with osteoporotic spine fracture treated with microsurgery.Results：During the followup of 90 patients for 6 months,16 patients were found to have fractures.The incidence of refracture was 17.78%.The results in the single factor analysis showed:age,gender,bone density,antiosteoporosis drugs used in accordance with the doctor’s advice,accidents during the recovery period,insufficient nutritional supply,bone cement leakage,calcium absorption disorders and diabetes mellitus were all related factors that affect postoperative refracture(P<0.05),multivariate Logistic regression analysis showed that female patients aged > 80 years,with bone cement leakage,bone density ≤-2.5SD and taking antiosteoporotic drugs without the doctor’s advice were all independent risk factors for refracture after surgery(OR=2.19,1.91,2.59,1.79,1.92,P<0.05).Conclusion：The incidence of postoperative fracture recurrence in elderly patients with osteoporotic spine fracture treated after minimally invasive surgery is relatively high,and the postoperative recurrence of fracture is affected by a variety of factors,so appropriate measures should be taken to prevent the recurrence of fracture in clinical practice.

Key words: minimally invasive surgery, osteoporosis, spinal fracture, recurring fracture