Abstract: Objective To compare the accuracy of 3D-Slicer software and traditional manual measuring method in preoperative localization of intracranial lesions.
Methods 40 patients diagnosed with intracranial lesions(brain tumors,cerebral hemorrhage,traumatic brain injury,foreign bodies,aneurysm,etc).and met the inclusion criteria were selected in our research.The image data of the patients were collected and analyzed by 3D-Slicer software on personal computers,resulting in visual data of three dimensional reconstruction.Then the data were imported into the mobile phone software “Sina”.The data was generated and applied in preoperative localization by the virtual reality(VR) glasses.At the same time,the traditional manual measuring method with the help of two dimensionalimage data and markers were applied during surgery.Finally,the accuracy of the two methods were measured and analysed.
Results Among the 40 cases,the preoperative localizations using the 3D-Slicer software was closer to intracranial lesions,with a mean distance of (0.24±0.14)cm from the center of the intracranial lesion.On the other hand,using traditional manual measuring method,the preoperative localizations were with a mean distance of (0.48±0.30)cm from the center of the intracranial lesion,the difference between the two methods was statistically significant(P<0.05).There was no damage to brain functional areas or important vascular structures in all the cases.
Conclusion Compared with the traditional manual measuring method,the localization using 3D-Slicer software is more accurate and convenient in preoperativelocalization.

Key words: 3D-Slicer software, intracranial lesions, preoperative localization